Tuesday, December 24, 2019
Death Be Not Proud - 1269 Words
J Singh English Coursework John Donne and Tony Harrison both discuss death in their poems. They were written in different eras and both poems have different views on this subject. John Donne had a rather privileged upbringing as he was born into a prosperous family and studied law at Oxbridge. Donne, however, was also unfortunate as he lost is father very early in his life and this could have affected his views on death. Tony Harrison on the other hand was born into a proud working class family in Leeds. Harrisonââ¬â¢s poem is completely opposite to Donneââ¬â¢s as it tells the reader about his personal life and the unfortunate passing of his Mother. ââ¬Å"Death be not Proudâ⬠was written three hundred and fifty years ago and written in sonnetâ⬠¦show more contentâ⬠¦Possibly the saddest feature of the poem is the fact that, although both Harrison and his father himself know that the father isnââ¬â¢t coping very well, neither of them can bring themselves to talk about it. This exposes the inability of men (especially old, proud Yorkshire men like Harrisonââ¬â¢s father) to speak openly about their feelings. Harrisonââ¬â¢s father would see it as a sign of weakness to openly show his great sorrow and his ââ¬Å"still raw loveâ⬠to his son. The word raw is used to describe his love as an undressed wound and the pain is still constant. The poem is therefore painfully well observed and frustratingly honest. We feel very sorry for Harrisonââ¬â¢s father and indeed for Harrison himself, who allowed his father to carry on the pretence without ever feeling able to help. His father is now dead, his phone number i s ââ¬Å"disconnectedâ⬠and it is too late for Harrison to ââ¬Å"callâ⬠. The final verse presents the reader with an antithetic juxtaposition. Harrison begins with stating that, ââ¬Å"I believe life ends with death, and that is allâ⬠, (this contrasts to Donne, as he doesnââ¬â¢t believe in the afterlife). However, his actions do not support his statement, as although his parents are both dead, he still keeps their memory alive in his ââ¬Å"new black leather phone bookâ⬠, still ââ¬Å"callingâ⬠their ââ¬Å"disconnected numberâ⬠. Harrisonââ¬â¢s behaviour is hugely ironic, given the almost critical way in which he exposed his fatherââ¬â¢s frailties in the opening three verses, now, just like hisShow MoreRelatedDeath Be Not Proud1025 Words à |à 5 PagesGreg Mohnkern ID: L23191458 WRITING STYLE USED: Essay of poetry (MLA style) Thesis Statement: ââ¬Å"Death be not proudâ⬠by John Donne personifies death, as its title aptly prescribes. Giving death human traits allows the writer to blast him with colorful images full of sarcasm and a tone of defiance. The ultimate message of the author provokes the human soul to resist the fear of death. Outline: Introduction: Thesis statement Transition: Discuss the writerââ¬â¢s life in relationshipRead MoreDeath, Be Not Proud1661 Words à |à 7 PagesDeath ââ¬Å"Death, be not proud (Holy Sonnet 10)â⬠by John Donne dramatizes the conflict between the perception and the reality of death, through the use of imagery. The speaker completely talks down the common perception of death, stating that even though many have called it ââ¬Å"mighty and dreadful,â⬠it really is not. The speaker compares death to sleep, which is generally an enjoyable thing. The personification of death is something that is popular in culture. Death is often depicted as a skeletal characterRead More Death Be Not Proud Essay821 Words à |à 4 Pagesto die? In the memoir Death Be Not Proud by John Gunther, his son Named Johnny is faced with this situation. At an early age, Johnny was found with a brain tumor, and struggles to survive. Johnny later died from the brain tumor. Johnny was loved by many people; much of whom tried his/her best to help Johnny through this ordeal. Although Johnny was faced with death, Johnny faced death with courage throughout the book. Even though Johnny was faced with death, he faced death with courage. Johnny showedRead MoreDeath, Be Not Proud by John Donne755 Words à |à 4 Pages In John Donneââ¬â¢s sonnet ââ¬Å"Death, Be Not Proudâ⬠death is closely examined and Donne writes about his views on death and his belief that people should not live in fear of death, but embrace it. ââ¬Å"Death, Be Not Proudâ⬠is a Shakespearean sonnet that consists of three quatrains and one concluding couplet, of which I individually analyzed each quatrain and the couplet to elucidate Donneââ¬â¢s arguments with death. Donne converses with death, and argues that death is not the universal destroyer of life. He elaboratesRead MoreDeath Be Not Proud By John Donne1329 Words à |à 6 PagesThe progression of societal beliefs regarding our approach towards death is dependent upon the changing nature of both cultural and historical contexts. In Donneââ¬â¢s Holy Sonnet ââ¬ËDeath be not proudââ¬â¢ he uses second person narration to address ââ¬Å"Deathâ⬠as ââ¬Å"thouâ⬠, ââ¬Å"theeâ⬠and ââ¬Å"thyâ⬠, death is not considered conceptually bu t anthropomorphised as the poems fundamental pride. In ââ¬ËDeath be not proudââ¬â¢, we see how the rumination of death is shaped by Elizabethan values. Through the subverted Petrarchan structureRead MoreDeath, Be Not Proud, By John Donne1303 Words à |à 6 PagesDeath and mortality are common themes widely used throughout poetry and other numerous works of literature. As well as this, death is a common occurrence in life, and though most people refuse to accept or acknowledge it, everyone must deal with it at some point in their lifetime. Whether it be the death of a family member, friend, or the final stages of your own life you will experience death in some way. In the poems, ââ¬Å"Death, be not proudâ⬠and ââ¬Å"Do Not Go Gentle into That Good Night,â⬠the speakersRead MoreDeath Be Not Proud By John Donne1908 Words à |à 8 PagesJohn Donneââ¬â¢s poem, ââ¬Å"Death Be Not Proudâ⬠(1633), is only one of the impressive poems in his collection: The Holy S onnets. In ââ¬Å"Death Be Not Proudâ⬠, Donne expresses his Anglican beliefs as he addresses deathââ¬â¢s fraudulent image and unjustified pride. Donneââ¬â¢s audience is death, but his poem is also intended for itsà readers, whoà ââ¬Å"some have called [death] / Mighty and dreadfulâ⬠(1-2). He begins the poem with a calm, conversational tone, but becomes more aggressive and expositive as his poem progresses.Read MoreJohn Donne Death Be Not Proud Analysis799 Words à |à 4 PagesIs Death the Finale? Death has always been an intriguing topic in literature. Writers have been confounded by the idea of death and the unknown afterlife for centuries. Some people believe death is the end of all things because nothing can withstand it. In John Donneââ¬â¢s poem, ââ¬Å"Death, be not proud,â⬠the poet explains his personal understanding of death and its permanence. This poem is a narrative sonnet. Although this sonnet follows the rhyme scheme of an Italian sonnet (abba cddc effe gg), it alsoRead MoreAnalysis Of Death Be Not Proud By John Donne745 Words à |à 3 PagesThe Holy Sonnet, ââ¬Å"Death Be Not Proudâ⬠written by John Donne. He was the founder of metaphysical poems in the Elizabeth period and a religious figure. A Metaphysical Poetic style maybe philosophical and spiritual subjects that were approached with reason and often concluded in paradox. Metaphysical poets examined serious questions about existence of God the Holy Sonnet 10 was one of nineteen other Holy So nnets he wrote. Donne was famous for his poems of life, death, and religion. This poem was writtenRead MoreAnalysis Of Death Be Not Proud By John Donne1488 Words à |à 6 PagesThroughout his poems, John Donne uses literary devices, such as imagery and diction, to discuss an overarching theme of death along with its religious implications, done most noticeably in the Holy Sonnet ââ¬Å"Death Be Not Proudâ⬠and the lyrical poem ââ¬Å"Hymn to God, My God, In My Sickness.â⬠He also elaborates on the complexity of emotion, particularly in the metaphysical love poem, ââ¬Å"The Flea.â⬠Donneââ¬â¢s witty and clever style paired with his affinity for social and religious commentary allows his works to
Monday, December 16, 2019
Paradise Lost and Adamââ¬â¢s response to the Gospel Free Essays
That all this good of evil shall produce, [470] And evil turn to good; more wonderful Then that which by creation first brought forth Light out of darkness! full of doubt I stand, Whether I should repent me now of sin By mee done and occasiond, or reJoyce [ 475 ] Much more, that much more good thereof shall spring, To God more glory, more good will to Men From God, and over wrauth grace shall abound. (Milton, 12. 469-477) The passage above is about Adam responding to Gabrielââ¬â¢s message about the Gospel. We will write a custom essay sample on Paradise Lost and Adamââ¬â¢s response to the Gospel or any similar topic only for you Order Now Gabriel has Just told Adam the story of how through Adam and Eveââ¬â¢s mistake Jesus overcame sin. ââ¬Å"But to the Cross he nailes thy Enemies,â⬠and ââ¬Å"Shall bruise the head of Satan, crush his strengthâ⬠(Milton, 12. 430,415). The news of Jesusââ¬â¢ gracious victory over sin and death overwhelms Adam. He responds in lines 471-472 by saying that the post-fallen world (with Jesus) is greater than the pre-fallen world in the Garden of Eden. Adam is basically saying he does not feel as bad for the fall ecause of the good that will ââ¬Å"springâ⬠(line 476) forth from it. I think this passage is very neat and speaks a whole lot to the work of Jesus in my life. So much evil has come from the fall, and sometimes I ask myself, ââ¬Å"if God is all- knowing, then why did he make humans when he knew that we would fall? â⬠The whole poem has helped me understand that ââ¬Å"whyââ¬â¢. Specifically the passage above ultimately, more good has come through Jesus, than bad has from sin and death! This takes some weight off my shoulders whenever I sin and fall short. I now see that Godââ¬â¢s grace and love is more powerful than anything bad that I can do. Jesus had slain sin and death, and I am victorious through Him. Even seeing Adamââ¬â¢s cheerfulness after the good news makes me see the fall of humankind differently; it reminds me to look at Jesus rather than at my sin. In my discussion with my friend about this passage and the poem as a whole, I learned the power of literature. This poem speaks not only about Christianity, but also about the history of beliefs. How to cite Paradise Lost and Adamââ¬â¢s response to the Gospel, Papers
Saturday, December 7, 2019
Amino Acid Becoming A Membrane Transporter free essay sample
Biology Oxford Presentation A. Entering the epithelia cell of the small intestine, until being loaded onto the proper tRNA. Amino acid present in the lumen of the small intestine The goal is to cross through the epithelial cell membrane to enter into the epithelial cellââ¬â¢s cytoplasm ââ¬â its charged cuz of side chains To get through the membrane the amino acid must cross the Simple columnar epithelial cells lining the apical surface of the small intestinal tract. These cells are impermeable to any harmful bacteria that may be ingested by the body, but permeable to necessary ions. Absorption of amino acids occurs through a process known as facilitated diffusion through membrane transporters (carrier protein) by means of active transport OR The type of transporter which an animo acids is transported through the epithelial membrane through depends on the R-group attacked to the particular amino acid (structure and combosition) These transporters bind amino acids only once they have bound sodium ions ââ¬â this is known as coupled transport This coupled transport is through a symport transporter protein which works by transporting the amino acid across the cell membrane only in the presence of a sodium ion (sodium is co-transported) Once the amino acid is released from the transporter protein into the cytoplasm of the epithelial cell the amino acids collect in pools until they are pick-up by tRNA that is floating throughout the cytoplasm The enzyme aminoacyl tRNA synthetase for that specific amino acid binds ATP and the amoni acid to the active site ATP is hydrolyzed inot AMP which then minds to the amino acid in the active site The tRNA for the specific amino acid comes into contact with the specific aminoacyl tRNA synthetase to collect the activated amino acid The amino acid uses the energy from the bonded AMP to transfer to the tRNA B. Initiation of translation, until incorporated into a folded protein Once the mature mRNA reaches the cytoplasm it will bind to the small subunit of the ribosome (ribosomes are organelles within the cell either free floating or attached to the ER, and are made of rRNA and proteins) Translation Initiation: Then the first tRNA lines up its anit-codon sequence to the corresponding codon sequence on the mRNA, which are specific to each amino acid, at the ââ¬Ëp-siteââ¬â¢ on the ribosome (the initiating tRNA will most likely be carrying the amino acid methionine) Initiation of translation is completed with the large subunit of the ribosome binds to the small unit Elongation: The next tRNA (with the correct aintcodon and carrying a specific amino acid) moves in a parks at the A-site A peptide bond forms between the two amino acids à The ribosome moves down the mRNA by one reading frame, which puts the first amino acid in the E-site (where the tRNA will exit, and the second amino acid moves into the P-site Now another tRNA can move into the empty A-site of the ribosome, and a new peptide bond forms between the new amino acid on the tRNA in the A-site, there by adding to the amino acid chain The ribosome moves over one frame, one amino acid exits, another enters, and another amino acid is added to the chain (the cycle continues) until I reaches a ââ¬Ëstopââ¬â¢ When the ribosome reaches a reading frame that reads for the ââ¬Ëstopââ¬â¢ sequence (one of three termination codons) which then signals to the ribosome that it is finished reading the mRNA strand Termination: The large and small subunits of the ribosome disengage from the mRNA strand, and release the amino acid sequence that will then go onto form its proper shape The folding of the protein has been taking place turning translation, before termination Folding takes place as a result of the hydrogen bonding and chemical interactions of the R-groups attached to the amino acids ââ¬â this folding c=occurs spontaneously (no energy required) Molecular chaperones may assist in the protein folding (some chaperones bind to the ribosome near the ââ¬Ëtunnelââ¬â¢ where growing peptide exits As a result of the H-bonding, and chemical iteraction of the R-groups ââ¬â aided by chaperones; the protein will fold into its correct specific shape C. Post translation modifications, until installation on the plasma membrane All protein syntheses takes place on free ribosomes Post translation modifications are chemical modifications of the protein structure (of the amino acids) which generally involves the addition of functional groups/ small molecules which increases protein diversity Some types of post-translational modifications Glycosylation ââ¬â addition of carbohydrate Lipoylation addition of lipid groups Phosphorylation addition of phosphate groups Ubiquitination ââ¬â addition of ubiquitin Methylation ââ¬â addition of methyl group Acetylation- addition of acetyl group Proteolysis- cleavage of peptide bonds â⬠¦Ã¢â¬ ¦over 30 different types of PTMs Once the protein has been modified the signal sequence, a stretch of amino acids, will direct the protein to particular organelles All protein transport requires energy The protein contains a signal sequence which makes the protein bound for the ER The signal recognition particle on the signal sequence binds to SRP receptor in the ER membrane- the SRP is displaced and recycled The soluble protein travels through the translocation channel into the ER lumen where it is covalently modified to stabilize the protein (disulfide bonds), leaving the signal sequence in the ER membrane The protein is kept in the ER until it is properly folded and helps to direct it to the proper organelle The properly folded protein the then packed in a budding transport vesicle and sent to the golgi apparatus The golgi apparatus accepts the protein on the cis-golgi network (modifications and removal of the CHO groups from ER and addition of new ones) and and is then sent through the apparatus until it reaches the trans golgi network- where is is packaged and secreted from the organelle The trans golgi network secrets the secretary vesicle (membrane bound vesicle filled with protein) through constructive secretion Theà vesicle travels to the cell membrane, and through unregulated membrane fusion, fusses to become apart of the plasma membrane, bringing with it the newly synthesized proteins that become apart of the plasma membrane
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